Endothelial cell alignment along the direction of laminar fluid flow is widely understood to be a defining morphological feature of vascular homeostasis. While the role of associated signaling and structural events have been well studied, associated intercellular stresses under laminar fluid shear have remained ill-defined and the role of these stresses in the alignment process has remained obs...

This paper describes laminar fluid flow through a three-dimensional elastomeric microstructure formed by two microfluidic channels, fabricated in layers that contact one another face-to-face (typically at a 90 degree angle), with the fluid flows in tangential contact. There are two ways to control fluid flow through these tangentially connected microchannels. First, the flow profiles through th...

Laminar and Turbulent Flow. If a fluid flows through a long, smooth-walled, narrow tube at a low flow rate, flow is likely to be “laminar.” Here the particles of fluid travel parallel to the sides of the tube. This is often the case for blood flowing in veins. Flow is proportional to the pressure difference (Figure 2A). The viscosity of the fluid is an important determinant of the relationship ...

In vortex motion fluid moves in curve path and the stream lines are curved. When the fluid flows between curved stream line, the centrifugal forces are setup which is counter balanced by pressure forces acting in the radial direction. The vortex motion has two types of curved motion. The first type called free vortex type, the fluid moves due to its own natural effect but energy is not added to...

In this paper, we present experimental investigation of convective heat transfer characteristic in the inner tube fluid of miniature concentric double tube Hair-pin heat exchanger with constant heat flux. This work is carried out for distilled water and a mixture of distilled water and ethylene glycol (10%, 20% and 25% by volume) as heat transfer cold fluid flowing in inner tube to carry away h...

A fluid-mechanical model is developed for the float-polishing process. In this model laminar flow between the sample and the lap results in pressure gradients at the grooves that support the sample on a fluid layer. The laminar fluid motion also produces supersmooth, damage-free surfaces. Quartz substrates for applications in high-stress environments were float polished, and their surfaces were...

We demonstrate a novel strategy for mixing solutions and initiating chemical reactions in microfluidic systems. This method utilizes highly focused nanosecond laser pulses from a Q-switched Nd:YAG laser at lambda = 532 nm to generate cavitation bubbles within 100- and 200-microm-wide microfluidic channels containing the parallel laminar flow of two fluids. The bubble expansion and subsequent co...

in this work a numerical study of thermal and fluid dynamics behavior of natural air convection in a square cavity in a laminar flow is presented, by finite volume method. the square cavity has two walls heated with different temperatures and two isolated walls. the numerical simulation is made up of several rayleigh numbers to . flow and isotherm lines are presented and analyzed. the numerical...